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Clinicopathologic correlations of renal pathology in the adult population of Poland

cris.lastimport.scopus2024-09-18T01:31:14Z
dc.abstract.enBackground. This is the first report on the epidemiology of bi opsy-proven kidney diseases in Poland. Methods. The Polish Registry of Renal Biopsies has collected information on all (n = 9394) native renal biopsies performed in Poland from 2009 to 2014. Patients’ clinical data collected at the time of biopsy, and histopathological diagnoses were used for epidemiological and clinicopathologic analysis. Results. There was a gradual increase in the number of native renal biopsies performed per million people (PMP) per year in Poland in 2009–14, starting from 36 PMP in 2009 to 44 PMP in 2014. A considerable variability between provinces in the mean number of biopsies performed in the period covered was found, ranging from 5 to 77 PMP/year. The most common renal bi opsy diagnoses in adults were immunoglobulin A nephropathy (IgAN) (20%), focal segmental glomerulosclerosis (FSGS) (15%) and membranous glomerulonephritis (MGN) (11%), whereas in children, minimal change disease (22%), IgAN (20%) and FSGS (10%) were dominant. Due to insufficient data on the paediatric population, the clinicopathologic analysis was limited to patients ≥18 years of age. At the time of renal biopsy, the majority of adult patients presented nephrotic range proteinuria (45.2%), followed by urinary abnormalities (38.3%), nephritic syndrome (13.8%) and isolated haematuria (1.7%). Among nephrotic patients, primary glomerulopathies dominated (67.6% in those 18–64 years of age and 62.4% in eld erly patients) with leading diagnoses being MGN (17.1%), FSGS (16.2%) and IgAN (13.0%) in the younger cohort and MGN (23.5%), amyloidosis (18.8%) and FSGS (16.8%) in the elderly cohort. Among nephritic patients 18–64 years of age, the majority (55.9%) suffered from primary glomerulopathies, with a predominance of IgAN (31.3%), FSGS (12.7%) and cres centic GN (CGN) (11.1%). Among elderly nephritic patients, primary and secondary glomerulopathies were equally com mon (41.9% each) and pauci-immune GN (24.7%), CGN (20.4%) and IgAN (14.0%) were predominant. In both adult co horts, urinary abnormalities were mostly related to primary glo merulopathies (66.8% in younger and 50% in elderly patients) and the leading diagnoses were IgAN (31.4%), FSGS (15.9%), lupus nephritis (10.7%) and FSGS (19.2%), MGN (15.1%) and pauci-immune GN (12.3%), respectively. There were sig nificant differences in clinical characteristics and renal biopsy findings between male and female adult patients. Conclusions. The registry data focused new light on the epi demiology of kidney diseases in Poland. These data should be used in future follow-up and prospective studies.
dc.affiliationNauk o Człowieku
dc.contributor.authorAgnieszka Perkowska-Ptasinska
dc.contributor.authorArtur Bartczak
dc.contributor.authorMalgorzata Wagrowska-Danilewicz
dc.contributor.authorAgnieszka Halon
dc.contributor.authorKrzysztof Okon
dc.contributor.authorAldona Wozniak
dc.contributor.authorMarian Danilewicz
dc.contributor.authorHenryk Karkoszka
dc.contributor.authorAndrzej Marszałek
dc.contributor.authorJolanta Kowalewska
dc.contributor.authorAndrzej Mroz
dc.contributor.authorAgnieszka Korolczuk
dc.contributor.authorAndrzej Oko
dc.contributor.authorAlicja Debska-Slizień
dc.contributor.authorBeata Naumnik
dc.contributor.authorZbigniew Hruby
dc.contributor.authorMarian Klinger
dc.contributor.authorKazimierz Ciechanowski
dc.contributor.authorMarek Myslak
dc.contributor.authorWladyslaw Sulowicz
dc.contributor.authorAndrzej Rydzewski
dc.contributor.authorAndrzej Wiecek
dc.contributor.authorJacek Manitius
dc.contributor.authorTadeusz Gregorczyk
dc.contributor.authorStanisław Niemczyk
dc.contributor.authorMichał Nowicki
dc.contributor.authorRyszard Gellert
dc.contributor.authorTomasz Stompor
dc.contributor.authorMonika Wieliczko
dc.contributor.authorKrzysztof Marczewski
dc.contributor.authorLeszek Paczek
dc.contributor.authorOlga Rostkowska
dc.contributor.authorDominika Deborska-Materkowska
dc.contributor.authorGrazyna Bogdanowicz
dc.contributor.authorAndrzej Milkowski
dc.contributor.authorMagdalena Durlik
dc.contributor.authorA. Pukaczewska-Woinska
dc.contributor.authorB. Naumnik
dc.contributor.authorJ. Kowalewska
dc.contributor.authorJ. Manitius
dc.contributor.authorA. Marszalek
dc.contributor.authorJ. Mesjasz
dc.contributor.authorP. Firczyk
dc.contributor.authorA. Debska-Slizien
dc.contributor.authorA. Wiecek
dc.contributor.authorH. Karkoszka
dc.contributor.authorJ. Dulawa
dc.contributor.authorW. Sulowicz
dc.contributor.authorA. Milkowski
dc.contributor.authorK. Okon
dc.contributor.authorW. Sydor
dc.contributor.authorA. Kirker-Nowak
dc.contributor.authorL. Kasprzak
dc.contributor.authorM. Wagrowska-Danilewicz
dc.contributor.authorM. Danilewicz
dc.contributor.authorM. Nowicki
dc.contributor.authorD. Moczulski
dc.contributor.authorJ. Rysz
dc.contributor.authorZ. Zbróg
dc.contributor.authorJ. Matych
dc.contributor.authorA. Ksiazek
dc.contributor.authorA. Korolczuk
dc.contributor.authorP. Kwiatkowski
dc.contributor.authorG. Bogdanowicz
dc.contributor.authorT. Stompor
dc.contributor.authorK. Cieszynski
dc.contributor.authorM. Kuriga
dc.contributor.authorA. Oko
dc.contributor.authorA. Wozniak
dc.contributor.authorA. Sokalski
dc.contributor.authorG. Swider
dc.contributor.authorW. Bentkowski
dc.contributor.authorA. Rakus
dc.contributor.authorZ. Gozdzik
dc.contributor.authorB. Hryniewicz
dc.contributor.authorK. Ciechanowski
dc.contributor.authorK. Dziewanowski
dc.contributor.authorM. Myslak
dc.contributor.authorA. Sydor
dc.contributor.authorM. Muszytowski
dc.contributor.authorA. Bartczak
dc.contributor.authorM. Durlik
dc.contributor.authorD. Deborska-Materkowska
dc.contributor.authorR. Gellert
dc.contributor.authorR. Malecki
dc.contributor.authorM. Wieliczko
dc.contributor.authorS. Niemczyk
dc.contributor.authorA. Perkowska-Ptasinska
dc.contributor.authorA. Mroz
dc.contributor.authorL. Paczek
dc.contributor.authorO. Rostkowska
dc.contributor.authorA. Rydzewski
dc.contributor.authorA. Halon
dc.contributor.authorZ. Hruby
dc.contributor.authorM. Klinger
dc.contributor.authorK. Marczewski
dc.contributor.authorJ. Piatkowski
dc.contributor.authorI. Habura
dc.date.accessioned2024-05-07T07:56:52Z
dc.date.available2024-05-07T07:56:52Z
dc.date.issued2017
dc.identifier.doi10.1093/ndt/gfw365
dc.identifier.issn0931-0509
dc.identifier.issn1460-2385
dc.identifier.urihttps://repo.akademiawsei.eu/handle/item/266
dc.languageen
dc.pbn.affiliationpsychology
dc.relation.ispartofNephrology Dialysis Transplantation
dc.rightsCC-BY-NC
dc.subject.enannual incidence of renal biopsy
dc.subject.enepidemiology of kidney diseases
dc.subject.englomerular diseases
dc.subject.enrenal biopsies registry
dc.subject.enrenal biopsy diagnoses
dc.titleClinicopathologic correlations of renal pathology in the adult population of Poland
dc.typeReviewArticle
dspace.entity.typePublication
oaire.citation.issuesuppl_2
oaire.citation.volume32